Assassin's Creed: Brotherhood is a third person action-adventure video game in development by Ubisoft for Microsoft Windows, PlayStation 3 and Xbox 360. The game is set to be released on 7 November 2010. The game is a direct-sequel to Assassin's Creed II and its story will take place shortly after the ending of the previous game, with Ezio returning as the main protagonist. It's the first game in the series to feature multiplayer mode. In May 2010, Ubisoft released the teaser trailer for the game. A cinematic trailer was revealed at E3 2010 along with gameplay. He will also have friends and ally assassins that can be played to make the game more challenging.

The game begins shortly after the events of Assassin's Creed II, in the year 1499. Monteriggioni is besieged by the Borgia clan, led by Rodrigo's son Cesare Borgia. During the battle Ezio's uncle, Mario, is killed and the Apple of Eden is taken by Borgia. Ezio, now a Master Assassin in the Assassin's Order, seeks revenge and heads to Roma (Rome) (1503) to take the fight to the Templar Order.

to be continued

E3 2010: The Eternal City Interview
E3 2010: Assembling the Brotherhood Interview

E3 2010: Multiplayer Demonstration Part I
E3 2010: Multiplayer Demonstration Part II